Preventable and controllable, heart disease is the leading cause of death for both men and women in the United States. The CDC reported, that an estimated 715,000 Americans suffer a heart attack and about 600,000 people die from heart disease each year in the US.
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Cocaine use is associated with several cardiovascular conditions including myocardial infarction, acute myocardial ischemia, arrhythmias, sudden death, and cardiomyopathy. These effects can be worsened when combined with alcohol consumption, while cardiomyopathy and arrhythmias can be caused by alcohol abuse alone. Studies also suggest that women suffer these consequences at lower doses of alcohol than do men. Reports have shown that amphetamine use causes many of the same cardiac problems as cocaine.
Source: http://www.samhsa.gov/co-occurring/topics/screening-andassessment/PhysicalHealthQuickFacts.pdf